Hexoral in Latin. Instructions for use of hexoral in spray, solution and tablets
Hexoral- a drug with antiseptic, antimicrobial, analgesic, hemostatic, enveloping and deodorizing properties. Active substance Hexorala- hexethidine.
It is characterized by a wide spectrum of activity against fungi, gram-negative and gram-positive microorganisms. By destroying the cell membrane of microorganisms and suppressing the oxidative reactions of bacterial metabolism, it contributes to their death. The activity of the drug against fungi is explained by its ability to disrupt the formation of compounds that form the membranes of the fungus.
Hexoral It is also effective in the treatment of infectious processes caused by protozoa or Pseudomonas aeruginosa.
Most strains of microorganisms are suppressed at a drug concentration of 100 mg/ml. No development of resistance was observed.
Therapeutic effect Hexorala observed from 10 to 12 hours.
When applied topically, Hexoral is practically not absorbed. Residual concentrations of the active components of the drug after a single use can be detected within 65 hours. Active concentrations of drug substances in samples from dental plaques can be determined within 14 hours after application of Hexoral.
Indications for use
Hexoral used for:- inflammatory diseases of the larynx and oral cavity (glossitis, gingivitis, periodontopathy, periodontal disease, infection of the dental lines and alveoli, stomatitis, aphthous stomatitis, tonsillitis, pharyngitis, sore throat, including Plaut-Vincent sore throat);
- fungal infections of the larynx and oral cavity;
- bleeding gums.
Hexoral use:
- as an adjuvant for acute respiratory viral infections;
- as a prophylactic agent: before surgery and in the postoperative period, for injuries of the larynx and oral cavity, for the prevention of superinfections;
- as a hygiene product: for oral hygiene in case of general diseases;
- as a deodorizing agent for bad breath (including conditions due to the disintegration of tumors of the larynx and oral cavity).
Mode of application
Hexoral solution should be used undiluted for washing or rinsing the throat and mouth, or applied to the affected areas of the mucous membrane using a tampon. The duration of the procedure is 0.5 minutes. For one procedure, 10-15 ml of solution should be used.Hexoral spray should be sprayed on the affected areas for 2 seconds.
Hexoral is prescribed twice a day. The drug should be taken after meals.
Side effects
When using Hexorala the development of allergic reactions and taste disturbances is possible. In cases of prolonged use of Hexoral, tooth discoloration may occur.Contraindications
Hexoral Contraindicated in case of individual hypersensitivity to the constituent drugs, children under three years of age (insufficient experience of use in pediatric practice).Pregnancy
No evidence of adverse effects Hexorala on the body of the fetus (child) or pregnant woman (nursing mother), however, due to insufficient data on the possibility of penetration of the drug components into breast milk or through the placental barrier, the use of the drug during lactation and pregnancy is possible only after a thorough analysis of the “potential harm” ratio for the fetus - benefit for the mother.”Interaction with other drugs
Clinically significant interactions of Hexoral with other drugs have not been described.Overdose
If a large amount of Hexoral is ingested, nausea and vomiting may develop, and therefore significant absorption of the drug is not expected.Theoretically, ingestion of the drug in large dosages by a child can lead to ethanol poisoning.
Treatment of overdose: gastric lavage (within two hours after poisoning), symptomatic therapy.
Release form
Hexoral solution 0.1% in bottles 100 ml.Hexoral aerosol 0.2% in an aerosol can of 40 ml.
Storage conditions
The storage temperature of Hexoral should not exceed 25 degrees Celsius.Keep away from light. Keep away from children.
Synonyms
Stomatidine, Hexetidine, Hexoral tabs.Compound
100 ml of Hexoral solution contains:0.1 g hexetidine.
Excipients: eucalyptus oil, anise oil, ethanol (96%), citric acid monohydrate, methyl salicylate, levomenthol, clove oil, sodium saccharin, peppermint oil, polysorbate 60, azorubine E122, purified water.
100 ml of Hexoral aerosol contains:
0.2 g hexetidine.
Excipients: citric acid monohydrate, sodium saccharin, macrogol lauryl ether, sodium hydroxide, mint flavor, glycerin, purified water, nitrogen.
Additionally
Hexoral does not affect the speed of reactions. When driving a vehicle, you should take into account the alcohol content: in the solution of the drug there is 4.73% alcohol, in the aerosol of the drug - 11.6% alcohol.Hexoral solution for rinsing the throat and mouth should be used only in cases where the patient can spit out the solution after rinsing.
Storing Hexoral in a cold place can lead to the formation of dot-shaped deposits on the walls of the bottle, which does not affect the activity and tolerability of the drug.
The drug Hexoral in the form of a solution can be used in children from an age when there is no danger of swallowing the solution.
Hexoral aerosol can be used to treat children from the age when they are able to hold their breath when the drug is injected.
Main settings
| Name: | HEXORAL |
| ATX code: | A01AB12 - |
Antiseptic for topical use in ENT practice and dentistry
Active substance
Release form, composition and packaging
◊ Aerosol for topical use 0.2% in the form of a clear, colorless liquid with a menthol odor.
Excipients: polysorbate 80, citric acid monohydrate, sodium saccharinate, levomenthol, oil, sodium calcium edetate, ethanol 96%, sodium hydroxide, purified water, nitrogen.
40 ml - aluminum aerosol cans (1) complete with one spray nozzle or four spray nozzles of different colors - cardboard packs.
pharmachologic effect
The effect of the drug Hexoral is associated with the suppression of oxidative reactions of bacterial metabolism (thiamine antagonist). The drug has a wide spectrum of antibacterial and antifungal effects, in particular against gram-positive bacteria and fungi of the genus Candida, but can also have an effect in the treatment of infections caused, for example, by Pseudomonas aeruginosa or Proteus spp. At a concentration of 100 mg/ml, the drug inhibits most strains of bacteria. No development of resistance was observed.
Hexethidine has a weak anesthetic effect on the mucous membrane.
The drug has an effect against influenza A viruses, respiratory syncytial virus (RS virus), herpes simplex virus type 1, affecting the respiratory tract.
Pharmacokinetics
Hexethidine adheres very well to the mucous membrane and is practically not absorbed.
After a single use of the drug, traces of the active substance are found on the mucous membrane of the gums within 65 hours. In dental plaque, active concentrations remain for 10-14 hours after use.
Indications
As a symptomatic remedy.
- symptomatic treatment for infectious and inflammatory diseases of the oral cavity and larynx:
Tonsillitis (including Plaut-Vincent angina, angina of the lateral ridges), pharyngitis, gingivitis, stomatitis, glossitis, periodontal disease;
Fungal diseases.
— prevention of infectious complications before and after surgical interventions in the oral cavity and larynx, as well as in case of injuries (including prevention of infection of the alveoli after tooth extraction);
— oral hygiene (including removal from the mouth).
Contraindications
- erosive-squamous lesions of the oral mucosa;
- children under 3 years of age;
- hypersensitivity to the components of the drug.
Dosage
The drug is used topically. Hexethidine adheres to the mucous membrane and due to this gives a lasting effect. In this regard, the drug should be used after meals.
U adults and children over 6 years old treat the affected areas while holding your breath. 1 injection for 1-2 seconds 2 times a day.
U children aged 3 to 6 years The use of the drug is possible after consultation with a medical professional.
The duration of treatment is determined by the doctor.
The drug is sprayed into the mouth or throat. Using an aerosol you can easily and quickly treat the affected areas. You need to do the following:
1. Place the spray nozzle on the aerosol can;
3. During administration of the drug, the bottle should be kept in an upright position at all times;
4. Inject the required amount of the drug by pressing on the head of the spray nozzle for 1-2 seconds, do not breathe when introducing the aerosol.
Side effects
Adverse reactions identified during post-registration use of the drug are classified as follows: very often (≥1/10), often (≥1/100,<1/10), нечасто (≥1/1000, <1/100), редко (≥1/10 000, <1/1000), очень редко (<1/10 000), частота неизвестна (частота возникновения не может быть оценена на основании имеющихся данных).
Allergic reactions: very rarely - hypersensitivity reactions (including urticaria), angioedema.
From the nervous system: very rarely - ageusia, dysgeusia.
From the respiratory system: very rarely - cough, shortness of breath due to the appearance of a hypersensitivity reaction.
From the digestive system: very rarely - dry mouth, dysphagia, nausea, enlarged salivary glands, vomiting.
Other: very rarely - reactions at the site of application (including irritation of the mucous membrane of the mouth and pharynx, burning sensation, paresthesia of the oral cavity, discoloration of the tongue, discoloration of teeth, inflammation, blistering and ulceration).
If any of the side effects indicated in the instructions are aggravated or other side effects are noted, the patient should consult a doctor.
Overdose
Hexethidine is unlikely to cause toxicity when used at recommended doses.
Symptoms: Ingestion of large quantities of a drug containing ethanol may result in signs/symptoms of alcohol intoxication.
Treatment: carrying out symptomatic therapy, as with alcohol intoxication. Gastric lavage is necessary within 2 hours after ingestion of an excess dose. In any case of overdose, the patient should immediately consult a doctor.
Drug interactions
Drug interactions with Hexoral aerosol have not been described.
special instructions
There are no special instructions.
The contents of the aerosol can are under pressure. Do not open, puncture or burn the container, even if it is empty.
If the medicine has become unusable or has expired, do not pour it into wastewater or throw it outside. It is necessary to place the medicine in a bag and place it in the trash container. These measures will help protect the environment.
Use in pediatrics
In children, the drug can be used from an age when there is no danger of uncontrolled swallowing or when they do not resist a foreign object (spray nozzle) in the mouth when using an aerosol and are able to hold their breath when injecting the drug.
Impact on the ability to drive vehicles and operate machinery
Hexoral aerosol does not affect the ability to drive vehicles or perform other potentially hazardous activities.
Pregnancy and lactation Storage conditions and periods
The drug should be stored out of the reach of children at a temperature not exceeding 25°C. Shelf life - 3 years. Do not use after the expiration date stated on the package.
The contents of the aerosol can should be used within 6 months after first use.
Composition and release form
in bottles with an aluminum screw cap of 200 ml; 1 bottle in a cardboard pack.
Description of the dosage form
Transparent red liquid with a mint smell.
pharmachologic effect
pharmachologic effect- deodorizing, enveloping, analgesic, hemostatic, antifungal, antiseptic.Pharmacodynamics
The antimicrobial effect of the drug Hexoral is associated with the suppression of oxidative reactions of bacterial metabolism (thiamine antagonist). The drug has a wide spectrum of antibacterial and antifungal action, in particular against gram-positive bacteria and fungi of the genus Candida, however, Hexoral may also have an effect in the treatment of infections caused by, for example, Pseudomonas aeruginosa or Proteus. At a concentration of 100 mg/ml, the drug inhibits most strains of bacteria. No development of resistance was observed. Hexethidine has a weak anesthetic effect on the mucous membrane.
Pharmacokinetics
Hexethidine adheres very well to the mucous membrane and is practically not absorbed.
After a single use of the active substance, traces of it are found on the gum mucosa within 65 hours. In plaques on teeth, active concentrations remain for 10-14 hours after application.
Indications for the drug Hexoral ®
inflammatory and infectious diseases of the oral cavity and pharynx;
severe, accompanied by fever or purulent diseases of the oral cavity and pharynx, requiring the prescription of antibiotics and sulfonamides, tonsillitis (in complex therapy);
tonsillitis (including tonsillitis with damage to the lateral ridges, Plaut-Vincent's tonsillitis);
pharyngitis;
gingivitis and bleeding gums;
periodontopathies (periodontal diseases and their symptoms);
stomatitis (inflammation of the oral mucosa), glossitis (inflammation of the tongue), aphthous ulcers (painful inflammation with superficial tissue defects) - to prevent superinfections;
infection of the alveoli (sockets of teeth) after tooth extraction;
fungal infections of the oral cavity and pharynx, especially candidal stomatitis (thrush);
before and after operations in the oral cavity and pharynx;
additional oral hygiene for general diseases;
elimination of bad breath, especially in the case of decaying tumors of the oral cavity and pharynx;
an aid in the treatment of colds.
Contraindications
hypersensitivity to any of the components of the drug;
children under 3 years of age.
Use during pregnancy and breastfeeding
There is no information about any harmful effects of the drug Hexoral during pregnancy and breastfeeding. However, before prescribing Hexoral to pregnant or lactating women, the doctor must carefully weigh the benefits and risks of treatment, given the lack of sufficient data on the penetration of the drug through the placenta and into breast milk.
Side effects
In some cases, hypersensitivity reactions to the drug developed. With prolonged use, taste disturbance may occur.
Directions for use and doses
Adults and children over 3 years old. Rinse the mouth and pharynx with 15 ml of undiluted solution for at least 30 s. Unless otherwise indicated, apply twice daily, preferably morning and evening. Hexethidine adheres to the mucous membrane and due to this gives a lasting effect. In this regard, the drug should be used after meals. The drug Hexoral solution for topical use is also safe with more frequent use.
The drug Hexoral solution for topical use can only be used for rinsing the mouth and throat. The solution should not be swallowed.
When rinsing, you should always use an undiluted solution.
When treating diseases of the oral cavity, the drug can also be applied using a tampon.
The duration of treatment is determined by the doctor.
Do not use in children under 3 years of age.
Overdose
Hexethidine in the indicated dosage is non-toxic. Ingestion of large quantities of the drug results in vomiting, so significant absorption is not expected. No cases of alcohol poisoning due to overdose have been described. Acute alcohol poisoning is very unlikely, but theoretically possible if a large dose of the drug is swallowed by a small child.
In any case of overdose, consult your doctor immediately.
Treatment: symptomatic, as with alcohol intoxication. Gastric lavage is necessary within 2 hours after ingestion of an excess dose.
special instructions
The drug Hexoral solution for topical use can be prescribed for rinsing the mouth and throat only if the patient can spit out the solution after rinsing.
Children can use the drug from an age when there is no danger of uncontrolled ingestion when using the solution.
The drug Hexoral solution for topical use contains ethanol 96% (4.33 g/100 ml of solution).
Storage conditions for the drug Hexoral ®
At a temperature not exceeding 25 °C. Protect from freezing.Keep out of the reach of children.
Shelf life of the drug Hexoral ®
2 years.Do not use after the expiration date stated on the package.
Synonyms of nosological groups
| ICD-10 rubric | Synonyms of diseases according to ICD-10 |
|---|---|
| A69.1 Other Vincent infections | Vincent's angina |
| Angina Plaut-Vincent | |
| Angina Simanovsky-Plaut-Vincent | |
| Sore throat, ulcerative membranous | |
| B37 Candidiasis | Visceral candidiasis |
| Invasive candidiasis | |
| Laryngeal candidiasis | |
| Candidiasis of the gastrointestinal tract | |
| Candidiasis of the skin and mucous membranes | |
| Candidiasis of mucous membranes and skin | |
| Candidiasis of the mucous membranes | |
| Candidiasis due to Candida albicans | |
| Candidomycosis | |
| Acute pseudomembranous candidiasis | |
| Chronic forms of candidiasis | |
| B37.0 Candidal stomatitis | Atrophic candidiasis of the oral cavity |
| Fungal diseases of the oral cavity | |
| Fungal infections of the mouth | |
| Fungal infectious | |
| Candidiasis of the gastrointestinal tract | |
| Candidiasis of the skin and mucous membranes of the mouth and pharynx | |
| Oral candidiasis | |
| Oral candidiasis | |
| Candidiasis with damage to the skin and mucous membranes | |
| Candidiasis of the oral mucosa | |
| Candidiasis of the mucous membranes | |
| Candidiasis of mucous membranes and skin | |
| Candidiasis of the mucous membranes of the oral cavity and pharynx | |
| Candidiasis of the oral cavity and pharynx | |
| Mucocutaneous candidiasis of the oral cavity | |
| Mycotic jam | |
| Oral thrush | |
| Oropharyngeal candidiasis | |
| Oropharyngeal candidiasis | |
| Chronic atrophic candidiasis of the oral cavity | |
| Chronic candidiasis of the mucous membranes | |
| J02.9 Acute pharyngitis, unspecified | Purulent pharyngitis |
| Lymphonodular pharyngitis | |
| Acute nasopharyngitis | |
| J03.9 Acute tonsillitis, unspecified (angina agranulocytic) | Angina |
| Sore throat, alimentary-hemorrhagic | |
| Sore throat secondary | |
| Primary tonsillitis | |
| Sore throat follicular | |
| Sore throats | |
| Bacterial tonsillitis | |
| Inflammatory diseases of the tonsils | |
| Throat infections | |
| Catarrhal sore throat | |
| Lacunar tonsillitis | |
| Acute sore throat | |
| Acute tonsillitis | |
| Tonsillitis | |
| Acute tonsillitis | |
| Tonsillar tonsillitis | |
| Follicular tonsillitis | |
| Follicular tonsillitis | |
| J06 Acute upper respiratory tract infections of multiple and unspecified localization | Bacterial infections of the upper respiratory tract |
| Bacterial respiratory infections | |
| Pain due to colds | |
| Pain in infectious and inflammatory diseases of the upper respiratory tract | |
| Viral respiratory disease | |
| Viral respiratory tract infections | |
| Inflammatory disease of the upper respiratory tract | |
| Inflammatory diseases of the upper respiratory tract | |
| Inflammatory diseases of the upper respiratory tract with difficult to separate sputum | |
| Inflammatory diseases of the respiratory tract | |
| Secondary infections with influenza | |
| Secondary infections due to colds | |
| Influenza conditions | |
| Difficulty secreting sputum in acute and chronic respiratory diseases | |
| Upper respiratory tract infections | |
| Upper respiratory tract infections | |
| Respiratory tract infections | |
| Respiratory and lung infections | |
| ENT infections | |
| Infectious and inflammatory diseases of the upper respiratory tract | |
| Infectious and inflammatory diseases of the upper respiratory tract and ENT organs | |
| Infectious and inflammatory diseases of the upper respiratory tract in adults and children | |
| Infectious and inflammatory diseases of the upper respiratory tract | |
| Infectious inflammation of the respiratory tract | |
| Respiratory tract infection | |
| Qatar of the upper respiratory tract | |
| Catarrhal inflammation of the upper respiratory tract | |
| Catarrhal disease of the upper respiratory tract | |
| Catarrhal phenomena from the upper respiratory tract | |
| Cough in diseases of the upper respiratory tract | |
| Cough with a cold | |
| Fever due to influenza | |
| ARVI | |
| acute respiratory infections | |
| Acute respiratory infection with symptoms of rhinitis | |
| Acute respiratory infection | |
| Acute infectious-inflammatory disease of the upper respiratory tract | |
| Acute cold | |
| Acute respiratory disease | |
| Acute respiratory disease of influenza nature | |
| Sore throat or nose | |
| Cold | |
| Colds | |
| Colds | |
| Respiratory infection | |
| Respiratory viral infections | |
| Respiratory diseases | |
| Respiratory infections | |
| Recurrent respiratory tract infections | |
| Seasonal colds | |
| Seasonal colds | |
| Frequent colds and viral diseases | |
| K05 Gingivitis and periodontal diseases | Inflammatory gum disease |
| Inflammatory diseases of the oral cavity | |
| Gingivitis | |
| Hyperplastic gingivitis | |
| Oral disease | |
| Catarrhal gingivitis | |
| Bleeding from gums | |
| Exacerbation of inflammatory diseases of the pharynx and oral cavity | |
| Epstein cysts | |
| Erythematous gingivitis | |
| Ulcerative gingivitis | |
| K06.8 Other specified changes in the gingiva and edentulous alveolar margin | Inflammation of the gingival margin |
| Bleeding from gums | |
| Bleeding gums | |
| Epstein cysts | |
| K10.3 Alveolitis of the jaws | Alveolitis |
| Post-extraction alveolitis | |
| K12.0 Recurrent oral aphthae | Aphthous stomatitis |
| Aphthous stomatitis | |
| Aphthae | |
| Aphthae of the oral mucosa | |
| Bednar afta | |
| Oral ulceration | |
| Ulceration of the oral mucosa | |
| Ulceration of the oral mucosa | |
| Recurrent aphthous stomatitis | |
| Aphthous stomatitis | |
| K13.7 Other and unspecified lesions of the oral mucosa | Aspirin burn of the oral mucosa |
| Sore gums when wearing dentures | |
| Oral inflammation | |
| Inflammation of the oral mucosa | |
| Inflammation of the oral mucosa after radiation therapy | |
| Inflammation of the oral mucosa after chemotherapy | |
| Inflammation of the oral mucosa | |
| Inflammation of the mucous membranes of the oral cavity | |
| Inflammatory diseases of the oral cavity | |
| Inflammatory process of the pharynx | |
| Disease of the oral mucosa | |
| Radioepithelitis | |
| Irritation from dentures | |
| Irritation of the oral mucosa by dentures and braces | |
| Oral wounds | |
| Sores from wearing dentures | |
| Injuries to the oral cavity and larynx | |
| Injuries to the oral mucosa | |
| Trophic diseases of the oral mucosa | |
| Trophic diseases of the oral mucosa | |
| Erosive and ulcerative periodontal lesions | |
| Erosive and ulcerative lesions of the oral mucosa | |
| Erosive and ulcerative periodontal lesions | |
| Erosive and ulcerative lesions of the oral mucosa | |
| Erosion of the oral mucosa | |
| Z100* CLASS XXII Surgical practice | Abdominal surgery |
| Adenomectomy | |
| Amputation | |
| Angioplasty of coronary arteries | |
| Carotid angioplasty | |
| Antiseptic treatment of skin for wounds | |
| Antiseptic hand treatment | |
| Appendectomy | |
| Atherectomy | |
| Balloon coronary angioplasty | |
| Vaginal hysterectomy | |
| Corona bypass | |
| Interventions on the vagina and cervix | |
| Bladder interventions | |
| Intervention in the oral cavity | |
| Restorative and reconstructive operations | |
| Hand hygiene of medical personnel | |
| Gynecological surgery | |
| Gynecological interventions | |
| Gynecological surgeries | |
| Hypovolemic shock during surgery | |
| Disinfection of purulent wounds | |
| Disinfection of wound edges | |
| Diagnostic interventions | |
| Diagnostic procedures | |
| Diathermocoagulation of the cervix | |
| Long surgical operations | |
| Replacing fistula catheters | |
| Infection during orthopedic surgery | |
| Artificial heart valve | |
| Cystectomy | |
| Short-term outpatient surgery | |
| Short-term operations | |
| Short term surgical procedures | |
| Cricothyroidotomy | |
| Blood loss during surgery | |
| Bleeding during surgery and in the postoperative period | |
| Culdocentesis | |
| Laser coagulation | |
| Laser coagulation | |
| Laser coagulation of the retina | |
| Laparoscopy | |
| Laparoscopy in gynecology | |
| CSF fistula | |
| Minor gynecological operations | |
| Minor surgical interventions | |
| Mastectomy and subsequent plastic surgery | |
| Mediastinotomy | |
| Microsurgical operations on the ear | |
| Mucogingival surgeries | |
| Stitching | |
| Minor surgeries | |
| Neurosurgical operation | |
| Immobilization of the eyeball in ophthalmic surgery | |
| Orchiectomy | |
| Complications after tooth extraction | |
| Pancreatectomy | |
| Pericardectomy | |
| Rehabilitation period after surgery | |
| The period of convalescence after surgical interventions | |
| Percutaneous transluminal coronary angioplasty | |
| Pleural thoracentesis | |
| Pneumonia postoperative and post-traumatic | |
| Preparing for surgical procedures | |
| Preparing for surgery | |
| Preparing the surgeon's hands before surgery | |
| Preparing the colon for surgery | |
| Postoperative aspiration pneumonia during neurosurgical and thoracic operations | |
| Postoperative nausea | |
| Postoperative bleeding | |
| Postoperative granuloma | |
| Postoperative shock | |
| Early postoperative period | |
| Myocardial revascularization | |
| Resection of the apex of the tooth root | |
| Gastric resection | |
| Bowel resection | |
| Resection of the uterus | |
| Liver resection | |
| Small bowel resection | |
| Resection of part of the stomach | |
| Reocclusion of the operated vessel | |
| Bonding tissue during surgery | |
| Removing stitches | |
| Condition after eye surgery | |
| Condition after surgery | |
| Condition after surgical interventions in the nasal cavity | |
| Condition after gastrectomy | |
| Condition after resection of the small intestine | |
| Condition after tonsillectomy | |
| Condition after removal of the duodenum | |
| Condition after phlebectomy | |
| Vascular surgery | |
| Splenectomy | |
| Sterilization of surgical instruments | |
| Sterilization of surgical instruments | |
| Sternotomy | |
| Dental operations | |
| Dental intervention on periodontal tissues | |
| Strumectomy | |
| Tonsillectomy | |
| Thoracic surgery | |
| Thoracic operations | |
| Total gastrectomy | |
| Transdermal intravascular coronary angioplasty | |
| Transurethral resection | |
| Turbinectomy | |
| Removal of a tooth | |
| Cataract removal | |
| Cyst removal | |
| Tonsil removal | |
| Removal of fibroids | |
| Removal of mobile baby teeth | |
| Removal of polyps | |
| Removing a broken tooth | |
| Removal of the uterine body | |
| Removing stitches | |
| Urethrotomy | |
| CSF duct fistula | |
| Frontoethmoidohaymorotomy | |
| Surgical infection | |
| Surgical treatment of chronic limb ulcers | |
| Surgery | |
| Surgery in the anal area | |
| Colon surgery | |
| Surgical practice | |
| Surgical procedure | |
| Surgical interventions | |
| Surgical interventions on the gastrointestinal tract | |
| Surgical interventions on the urinary tract | |
| Surgical interventions on the urinary system | |
| Surgical interventions on the genitourinary system | |
| Heart surgery | |
| Surgical procedures | |
| Surgical operations | |
| Vein surgery | |
| Surgical intervention | |
| Vascular surgery | |
| Surgical treatment of thrombosis | |
| Surgery | |
| Cholecystectomy | |
| Partial gastrectomy | |
| Transperitoneal hysterectomy | |
| Percutaneous transluminal coronary angioplasty | |
| Percutaneous transluminal angioplasty | |
| Coronary artery bypass surgery | |
| Tooth extraction | |
| Extirpation of baby teeth | |
| Pulp extirpation | |
| Extracorporeal circulation | |
| Tooth extraction | |
| Tooth extraction | |
| Cataract extraction | |
| Electrocoagulation | |
| Endourological interventions | |
| Episiotomy | |
| Ethmoidotomy |
In this article you can read the instructions for use of the drug Hexoral. Reviews of site visitors - consumers of this medicine, as well as the opinions of specialist doctors on the use of Hexoral in their practice are presented. We kindly ask you to actively add your reviews about the drug: whether the medicine helped or did not help get rid of the disease, what complications and side effects were observed, perhaps not stated by the manufacturer in the annotation. Analogues of Hexoral in the presence of existing structural analogues. Use for the treatment of sore throat, pharyngitis and gingivitis in adults, children, as well as during pregnancy and lactation.
Hexoral- an antiseptic drug for local use in ENT practice and dentistry. The antimicrobial effect of the drug is associated with the suppression of oxidative reactions of bacterial metabolism (thiamine antagonist).
The drug has a wide spectrum of antibacterial action (including against gram-positive bacteria) and antifungal action (including against fungi of the genus Candida).
Hexoral may also have an effect in the treatment of infections caused by Pseudomonas aeruginosa or Proteus.
At a concentration of 100 mg/ml, the drug inhibits most strains of bacteria. No development of resistance was observed.
Hexetidine (the active ingredient of the drug Hexoral) has a weak anesthetic effect on the mucous membrane.
Compound
Hexethidine + excipients.
Chlorhexidine dihydrochloride + benzocaine + excipients (Hexoral Tabs tablets).
Pharmacokinetics
Hexoral adheres very well to the mucous membrane and is practically not absorbed.
After a single use, the active substance is detected on the mucous membrane of the gums for 65 hours. In plaques on the teeth, active concentrations remain for 10-14 hours after application.
Indications
- inflammatory and infectious diseases of the oral cavity and pharynx;
- in the complex treatment of severe febrile or purulent diseases of the oral cavity and pharynx, requiring the use of antibiotics and sulfonamides, tonsillitis;
- tonsillitis (including tonsillitis with damage to the lateral ridges, Plaut-Vincent tonsillitis);
- pharyngitis;
- gingivitis and bleeding gums;
- periodontopathies, periodontal diseases and their symptoms;
- stomatitis, glossitis, aphthous ulcers to prevent superinfections;
- infection of the alveoli after tooth extraction;
- fungal infections of the oral cavity and pharynx, especially candidal stomatitis;
- before and after operations in the oral cavity and pharynx;
- additional oral hygiene for general diseases;
- elimination of bad breath, especially in the case of decaying tumors of the oral cavity and pharynx;
- an aid in the treatment of colds.
Release forms
Aerosol for topical use 0.2% (sometimes mistakenly called a spray).
Solution for topical use 0.1%.
Lozenges Geksoral tabs.
Instructions for use and method of use
The drug is applied topically.
When using an aerosol for topical use in adults and children over 3 years of age, a single dose is administered over 1-2 seconds.
When using a solution for topical use, rinse the mouth and throat with 15 ml of undiluted solution for 30 seconds.
The drug is prescribed 2 times a day (preferably in the morning and evening), after meals. Safe with more frequent use. Hexethidine adheres to the mucous membrane and due to this gives a lasting effect. In this regard, the drug should be used after meals.
The duration of treatment is determined by the doctor.
Rules for using the drug
When using a topical aerosol, the drug is sprayed into the mouth or throat. Using an aerosol you can easily and quickly treat the affected areas. You need to do the following:
1. Place the aerosol tube into the corresponding hole in the upper part of the bottle, lightly pressing on it, and point the tip of the tube away from you.
2. Hold the aerosol tube and direct it to the affected area of the mouth or pharynx.
3. During administration, the bottle should be kept in an upright position at all times.
4. Inject the required amount of the drug by pressing on the head for 1-2 s, do not breathe while administering the aerosol.
The topical solution can only be used to rinse the mouth and throat. The solution should not be swallowed. When rinsing, you should always use an undiluted solution. When treating diseases of the oral cavity, the solution can also be applied using a tampon.
Pills
The tablet should be slowly dissolved in the mouth until completely dissolved.
The drug should be started immediately after the first symptoms of the disease appear and continued for several days after the symptoms disappear.
Adults and children over 12 years of age are prescribed 1 tablet every 1-2 hours as needed, but not more than 8 tablets per day.
Children aged 4-12 years are prescribed up to 4 tablets per day.
Side effect
- hypersensitivity reactions to the drug;
- with prolonged use, taste disturbance may occur.
Contraindications
- children under 3 years of age;
- hypersensitivity to any of the components of the drug.
Use during pregnancy and breastfeeding
There is no data on any damaging effects of the drug Hexoral during pregnancy and lactation. However, before prescribing Hexoral to pregnant or lactating women, the doctor must carefully weigh the benefits and risks of treatment, given the lack of sufficient data on the penetration of the drug through the placental barrier and into breast milk.
special instructions
The drug Hexoral in the form of a solution for topical use can be used to rinse the mouth and throat only if the patient can spit out the solution after rinsing.
The drug Hexoral solution for topical use contains alcohol - ethanol 96% (4.33 g/100 ml of solution).
Use in pediatrics
Children can use the drug from an age when there is no danger of uncontrolled swallowing when using the solution and topical aerosol or when they do not resist a foreign object (applicator) in the mouth when using a topical aerosol and are able to hold their breath when the drug is injected.
Drug interactions
Benzocaine, due to the formation of its metabolite 4-aminobenzoic acid, reduces the antibacterial activity of sulfonamides and aminosalicylates.
Sucrose, polysorbate 80, insoluble salts of magnesium, zinc and calcium reduce the effect of chlorhexidine.
Analogues of the drug Hexoral
Structural analogues of the active substance:
- Maxisprey;
- Stomatidin;
- Stopangin.
If there are no analogues of the drug for the active substance, you can follow the links below to the diseases for which the corresponding drug helps, and look at the available analogues for the therapeutic effect.
Choosing the optimal medication for treating a child is a responsible task that should only be trusted to a qualified doctor. For some pathological processes, pediatricians recommend Hexoral. What does it contain, how does the product work, in what cases is it prescribed? How to give it correctly and what can be replaced – let’s figure it out together.
Composition and release forms of the drug
The main component of Hexoral, which ensures its pharmacological action, is the substance hexetidine. Depending on the form of release of the drug, its content will differ. A transparent reddish solution with a pleasant mild odor contains 100 mg of the active ingredient, while its concentration in a transparent aerosol with a menthol odor is twice as high. The tablets contain chlorhexidine and benzocaine.
Operating principle
In accordance with the instructions for use, Hexoral in any pharmacological form is a broad-spectrum antiseptic with a large list of indications. It acts on mucous membranes as a weak anesthetic. Its mechanism of action is based on suppressing the metabolic processes of bacteria.
The use of this medication is considered safe if the patient has no contraindications. Hexoral is not addictive, and pathogenic microorganisms do not develop resistance to its effects even with prolonged use. This makes it possible to carry out a course of treatment of the required duration without fear of negative consequences.
For what diseases is Hexoral prescribed to a child?
Hexoral for children is prescribed by a pediatrician strictly when indicated. How many years has it been used? In accordance with the instructions, the medicine is not prescribed for the treatment of children under 3 years of age.
The list of diseases for which Hexoral is prescribed to children is similar to the list of indications for the treatment of adults. The drug is often prescribed as part of a comprehensive treatment for colds and throat diseases. The use of Hexoral is also indicated for the following pathological conditions:
- neutralization of unpleasant odor from the oral cavity of any etiology;
- additional hygiene for systemic diseases;
- before and after any surgery in the oral cavity and pharynx;
- damage to the alveoli by infection after tooth extraction;
- fungus on the mucous membranes of the mouth and pharynx;
- stomatitis;
- glossitis;
- prevention of superinfections;
- aphthous ulcers in the mouth;
- bleeding gums;
- periodontopathy;
- pharyngitis;
- tonsillitis;
- angina;
- severe purulent and febrile diseases of the oral cavity and pharynx (as part of complex therapy along with sulfonamides and antibiotic therapy);
- infectious inflammation in the mouth and pharynx.
The drug is used for throat diseases of various etiologies Instructions for use for children
Hexoral in any form is taken only after meals or no earlier than 1-1.5 hours before meals.
- Rinse the throat and oral cavity with the solution. In accordance with the instructions for use, 1.5 tbsp should be used for the procedure. l. (15 ml) product. Rinse duration is 0.5 minutes. Repeat the procedure twice a day. The duration of the course of treatment is determined by the doctor.
- When treating pathological processes in the oral cavity, a tampon is soaked in a solution and applied to the affected areas. The recommended number of procedures per day is 2, but it is permissible to use the medicine more often, since it is safe and does not cause addiction or resistance in bacteria and fungi.
- Hexoral in aerosol form is applied to the pharynx and oral cavity by spraying. To get the recommended volume of the drug onto the mucous membranes, spraying should be carried out for 1-2 seconds. This dosage form is also used at least 2 times a day. The maximum number of procedures is determined by the doctor.
- To carry out a procedure using a spray, it is required that the baby be able to hold his breath for a short time at the request of mom or dad and not resist the spray. If these conditions are met, the drug can be used in the treatment of children under 3 years of age.
The drug should be used strictly according to the instructions A step-by-step description of the procedure for children is as follows:
- Explain to your child the essence of the future procedure, practice holding your breath for a few seconds on command;
- prepare a toy or book to distract the child from unpleasant sensations (not all children like the menthol taste of Hexoral);
- ask the small patient to open his mouth;
- take the bottle and turn it straight up with the nozzle;
- shallowly insert the spray nozzle into the child’s oral cavity;
- ask the baby to hold his breath;
- spray for 1 second;
- remove the nozzle from the child's mouth.
Hexoral in the form of lozenges is indicated for children over 4 years of age. It is already possible to explain to a child at this age that the pill should not be swallowed, but gradually dissolved.
Contraindications and side effects
The drug is not recommended for use in the treatment of children under 3 years of age. The drug is also contraindicated for persons suffering from hypersensitivity to hexethidine or auxiliary components. When using the medicine, it should be taken into account that it contains ethanol with a concentration of 96%.
Hexoral is considered one of the safest drugs; side effects with its use rarely occur. With a long course of treatment, patients sometimes develop taste disturbances. In rare cases, hypersensitivity reactions to the components occur.
The active ingredient in the dosage specified by the manufacturer in the instructions does not have a toxic effect on the human body. When an overdose is swallowed, the patient begins to vomit severely, so the medicine does not have time to be absorbed into the mucous membranes and does not cause significant harm to the body.
Despite the fact that Hexoral contains highly concentrated ethanol, there have been no cases of alcohol poisoning when a large dose was ingested.
If a child accidentally swallows the medicine, symptomatic treatment is carried out within two hours from this moment, first of all - gastric lavage.
Interaction with other drugs
The manufacturer does not provide information regarding the interaction of Hexoral with other medications. In accordance with the instructions for use, the drug can be used as an addition to antibiotic therapy and is well compatible with sulfonamides (does not suppress their effect and does not increase the likelihood of side effects).
Price and analogues
The cost of the drug will depend on the form of release. The average price of Hexoral solution varies from 210 to 240 rubles, while the medicine in the form of an aerosol for the throat will cost 240-260 rubles.
The choice of the analogue that is optimally suitable for a particular case should be entrusted to a qualified doctor. Pharmacy chains offer the following drugs:
| Drug name | Active ingredient | Release form | Age restrictions | Average price, rubles |
| Inhalipt (we recommend reading:) |
| Aerosol | From 3 years old. Can be used from 1 year of age as prescribed by a doctor. | 70-95 |
| Stomatidin | Hexetidine | Alcohol solution for topical use | From 5 years | 200-240 |
| Stopangin |
| Solution, spray | From 8 years old | Solution – 120-140, spray – 200. |
| Angi sept |
| Lozenges (see also:) | From 5 years | 200 |
Ingalipt spray is considered the main competitor of Hexoral due to its affordable cost - Ingalipt is almost three times cheaper (we recommend reading:). However, the main disadvantage of Ingalipt is considered to be a narrow list of indications for use, that is, for some diseases it cannot become a full replacement for the more expensive Hexoral.
Most analogue drugs are prohibited for use in the treatment of children under 4-5 years of age. For this reason, Hexoral is popular among parents of babies who require drug therapy at an earlier age. The low likelihood of side effects helps maintain high demand for the drug.